Right now, we are looking for people ages 18 and up with current foot pain due to plantar fibromatosis to participate in our research study. If you have been diagnosed with plantar fibromatosis and have one or two painful nodules in (in or on) the bottom of your foot, please continue reading to learn about potential participation in The STRIDE Study.
To see if there is a STRIDE study center in a city near you, please review the list below then complete the pre-qualification questionnaire on the home page.
If you would like to learn more about The STRIDE Study or participation in clinical research studies in general, please scroll down or click on the page links listed above.
To see if you may qualify to participate in our study, please take our pre-qualification questionnaire. If you prequalify on the questionnaire, you will have the option to submit your contact information to the nearest participating study center. If you submit your information, the study center staff will contact you for additional information. Based on this information, you may be asked to come to the study center to undergo additional assessments to determine whether you are eligible for the study. You are not obligated to participate in the study at any point in the process.
According to the National Institutes of Health, plantar fibromatosis, also called Ledderhose disease, is a disorder that results in the formation of nodules (fibromas) along the plantar fascia, the long ligament stretching from the heel to the toes. These nodules can cause pain, problems with walking and daily functioning, and decreased quality of life.
There is currently no available therapy that can impact disease progression. Current treatment of plantar fibromatosis is aimed at symptom relief and can vary depending on the severity of the disease. To help reduce the symptoms caused by plantar fibromatosis, doctors have a few options when prescribing treatment strategies. However, these treatments may not work for everyone with plantar fibromatosis. When conservative treatments fail, surgical removal of the nodules is often performed. However, recurrence of the nodules may occur even after surgical treatments.
For these reasons, it is important that doctors and scientists continue the search for new treatments for plantar fibromatosis.
Before investigational medications can be approved for public use, they must be tested in research studies like this one. If you have one or two painful nodules on the bottom of one foot from plantar fibromatosis, please consider participating in The STRIDE Study.
A research study (sometimes called “clinical research” or a “clinical trial”) is generally considered to be health-related research in people who have a specific condition, which uses a pre-defined written set of instructions and guidelines (the “protocol”) for how the study is to be conducted.